Advanced Search

Journal Navigation

Journal Home

Subscriptions

Archive

Contact Us

Table of Contents

SAGETRACK
Reproductive Sciences
This Article
Right arrow Full Text (PDF)
Right arrow References
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Saved Citations
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Request Reprints
Right arrow Add to My Marked Citations
Citing Articles
Right arrow Citing Articles via Google Scholar
Right arrow Citing Articles via Scopus
Google Scholar
Right arrow Articles by Lommerse, T.
Right arrow Articles by Peeters, L. L.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Lommerse, T.
Right arrow Articles by Aardenburg, R.
Right arrow Articles by Houben, A.
Right arrow Articles by Peeters, L. L.
Right arrowPubmed/NCBI databases
Medline Plus Health Information
*High Risk Pregnancy
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati  
What's this?

Endothelium-Dependent Vasodilatation in Formerly Preeclamptic Women Correlates Inversely With Body Mass Index and Varies Independently of Plasma Volume

Tessa Lommerse, MD

Department of Obstetrics and Gynecology, University of Maastricht, Maatricht, The Netherlands

Robert Aardenburg, MD

Department of Obstetrics and Gynecology, University of Maastricht, Maatricht, The Netherlands, robert{at}aardenburg.org

Alphons Houben, PhD

Department of Internal Medicine, University of Maastricht, Maastricht, The Netherlands

Louis L. Peeters, MD, PhD

Department of Obstetrics and Gynecology, University of Maastricht, Maatricht, The Netherlands

Endothelial dysfunction and a subnormal plasma volume predispose to preeclampsia. The authors determine whether endothelium-dependent vasodilatation is lower in formerly preeclamptic women, explore whether endothelial dysfunction coincides with low plasma volume, and determine if endothelial dysfunction correlates with circulating endothelial stressors. In formerly preeclamptic women and controls, the authors estimated changes in forearm blood flow after arterial occlusion. They measured plasma volume, blood pressure, and circulating variables. To identify factors associated with endothelial function, the authors used Spearman correlation and regression analysis. Endothelial function did not differ between patients and controls and did not correlate with plasma volume; however, it did correlate negatively with body mass index and positively with arterial compliance. Analysis suggested a negative impact of metabolic syndrome on endothelial function. In formerly preeclamptic women, endothelial function is comparable to controls and varies independently of plasma volume. In patients, endothelial function does vary with features of the metabolic syndrome.

Key Words: Preeclampsia • plasma volume • endothelial function.

Reproductive Sciences, Vol. 14, No. 8, 765-770 (2007)
DOI: 10.1177/1933719107308336
Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati    What's this?