Reproductive Sciences

 

Advanced Search

Journal Navigation

Journal Home

Subscriptions

Archive

Contact Us

Table of Contents

http://mc.manuscriptcentral.com/rsci

Click here for more information

Sign In to gain access to subscriptions and/or personal tools.
This Article
Right arrow Full Text (PDF)
Right arrow References
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Saved Citations
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Request Reprints
Right arrow Add to My Marked Citations
Citing Articles
Right arrow Citing Articles via ISI Web of Science (1)
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by De Matteo, R.
Right arrow Articles by Harding, R.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati  
What's this?
Reproductive Sciences, Vol. 15, No. 1, 66-74 (2008)
DOI: 10.1177/1933719107307716
© 2008 SAGE Publications

The Perinatal Development of Arterial Pressure in Sheep: Effects of Low Birth Weight Due to Twinning

Robert De Matteo, PhD

Department of Anatomy & Cell Biology, Monash University, Victoria, Australia, robert.dematteo{at}med.monash.edu.au

Victoria Stacy, BSc

Department of Anatomy & Cell Biology, Monash University, Victoria, Australia

Megan Probyn, PhD

Department of Anatomy & Cell Biology, Monash University, Victoria, Australia

Mina Desai, PhD

Harbor-UCLA Medical Center, Torrance, California

Michael Ross, MD

Harbor-UCLA Medical Center, Torrance, California

Richard Harding, PhD, DSc

Department of Anatomy & Cell Biology, Monash University, Victoria, Australia

The aim of this study is to determine the effect of fetal growth restriction due to twinning on the perinatal development of arterial pressure. Arterial pressure was recorded in fetal sheep (5 singletons, 8 twins) during late gestation and at 8 weeks after birth (11 singletons, 18 twins). In fetuses, there were no differences between singletons and twins in arterial pressure or plasma electrolytes. Postnatal twins were 17.3% lighter than singletons at birth, and growth rate was similar to singletons up to 8 weeks. After birth, arterial pressure was not different between groups, except that at 8 weeks, the systolic pressure was lower in twins. After birth, there were no differences between twins and singleton lambs in concentrations of plasma electrolytes, plasma renin, angiotensin II, and cortisol. Taken together with previous findings, the authors conclude that natural twinning in sheep followed by normal postnatal growth does not lead to hypertension.

Key Words: Twins • arterial pressure,renin • angiotensin II • cortisol • electrolytes.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati    What's this?