This Article Full Text (PDF) All Versions of this Article: 1933719109341843v1 16/11/1091    most recent References Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via Scopus Google Scholar Articles by Hale, S. A. Articles by Bernstein, I. M. PubMed PubMed Citation Articles by Hale, S. A. Articles by Schonberg, A. Articles by Badger, G. J. Articles by Bernstein, I. M. Social Bookmarking                         What's this?

Relationship Between Prepregnancy and Early Pregnancy Uterine Blood Flow and Resistance Index

Department of Obstetrics, Gynecology and Reproductive Sciences, University of Vermont, Burlington, Vermont

Adrienne Schonberg, RN

Department of Obstetrics, Gynecology and Reproductive Sciences, University of Vermont, Burlington, Vermont

Gary J. Badger, MS

Department of Medical Biostatistics, University of Vermont, Burlington, Vermont

Ira M. Bernstein, MD

Department of Obstetrics, Gynecology and Reproductive Sciences, University of Vermont, Burlington, Vermont, ira.bernstein{at}uvm.edu

We evaluated the relationship between prepregnancy and early pregnancy uterine blood flow (UBF) and resistance index (RI). Nineteen nulliparous participants were studied during cycle day 8 + 4, and early pregnancy (13.4 + 1.6 weeks). Color Doppler ultrasound of both uterine arteries and maternal heart was performed to calculate uterine RI, volumetric UBF, and cardiac output (CO), respectively. We observed a strong negative association of uterine RI with prepregnancy UBF (r = —.82, P < .001) that weakened, but remained significant in early pregnancy (r =—.48, P = .04). Prepregnancy uterine index (UBF/CO) was significantly associated with early pregnancy uterine index; r = .48, P = .04). There was also a trend associating prepregnancy and early pregnancy volumetric UBF (r = .44, P = .068). Prepregnancy UBF may be a determinant of early pregnancy UBF and UBF may have independent value as a predictor of adverse pregnancy outcome.

Key Words: Prepregnancy • pregnancy • uterine blood flow • resistance index • uterine hemodynamics.

This version was published on November 1, 2009

Reproductive Sciences, Vol. 16, No. 11, 1091-1096 (2009)
DOI: 10.1177/1933719109341843


CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter    What's this?