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Journal of the Society for Gynecologic Investigation
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Calibration of a Reflectance Pulse Oximeter in Fetal Lambs for Arterial Oxygen Saturations Below 70%

Anthony M. Carter, PhD

Department of Physiology, University of Odense, Denmark; Division of Perinatal Physiology, Department of Obstetrics, University Hospital, Zurich, Switzerland

Ruth Stiller, MD

Department of Physiology, University of Odense, Denmark; Division of Perinatal Physiology, Department of Obstetrics, University Hospital, Zurich, Switzerland; Division of Perinatal Physiology, Department of Obstetrics, University Hospital, Frauenklinikstrasse 10, CH-8091 Zurich, Switzerland rub{at}fhk.smtp.usz.ch

Volker König, PhD

Jan S. Jørgensen, MD, PhD

Per Svendsen, MSc, DVM

Renate Huch, MD

Department of Physiology, University of Odense, Denmark; Division of Perinatal Physiology, Department of Obstetrics, University Hospital, Zurich, Switzerland

Objective: To calibrate a reflectance pulse oximeter developed at the Division of Perinatal Physiology, University Hospital of Zurich, for monitoring of oxygen saturations below 70%.

Methods: Oxygen saturation measured monivasively with the reflectance pulse oximeter in fetal sheep was compared with oxygen saturation of arterial blood samples measured by a conventional two-wavelength oximeter. Oxygen saturation was varied by stepwise reduction of the inspired oxygen concentration of the ewe.

Results: A total of 58 data pairs was obtained from five fetuses, with a range of 10.9-73.5% for the reference method and 6.8-69.2% for the pulse oximetry oxygen saturation values. There was good correlation between the results obtained by the two methods (r2 = .89, P < .0001), with a 95% confidence interval of ± 12.5%. The pulse oximeter showed a precision of 6.2% oxygen saturation.

Conclusion: The Zurich reflectance pulse oximeter offers valid measurements of oxygen saturation levels down to 10% oxygen saturation, and is therefore suitable for monitoring the fetus during delivery.

Key Words: Pulse oximetry • arterial oxygen saturation • fetal lambs • calibration

Journal of the Society for Gynecologic Investigation, Vol. 5, No. 5, 255-259 (1998)
DOI: 10.1177/107155769800500506


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